Synoxyl® AZ – Advanced Antioxidant Protection with Acetyl Zingerone
Synoxyl® AZ – Advanced Antioxidant Protection with Acetyl Zingerone
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Synoxyl® AZ – Advanced Antioxidant Protection with Acetyl Zingerone

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1. What is Synoxyl® AZ and How is it Used in Cosmetics?

Synoxyl® AZ is a patented, multifunctional skincare ingredient designed to target visible skin aging caused by environmental stress. Its key active, Acetyl Zingerone, is a scientifically engineered antioxidant inspired by zingerone, a bioactive molecule derived from ginger. Acetyl Zingerone is known for its superior free radical scavenging capabilities and exceptional photostability.

In cosmetic formulations, Synoxyl® AZ is prized for its ability to:

  • Neutralize oxidative stress from UV and pollution.

  • Protect against visible signs of photoaging.

  • Stabilize light- and oxygen-sensitive ingredients (like Vitamin C and retinol).

  • Enhance skin brightness and reduce the look of uneven tone.

Its multifunctional performance makes it ideal for clean, active-forward skincare formulations.


2. Synoxyl® AZ Technical Details and Characteristics

  • INCI Name: Acetyl Zingerone

  • CAS Number: 56984-25-9

  • Appearance: Light yellow to amber powder or viscous liquid (form may vary by supplier)

  • Solubility: Oil-soluble

  • Recommended Usage Rate: 0.1% – 1.0%

  • pH Stability: 4.0 – 8.0

  • Functions:

    • Potent antioxidant

    • Skin-protectant

    • Photostabilizer for UV filters and sensitive actives

    • Brightening and tone-evening support

  • Compatibility:

    • Compatible with esters, natural oils, silicones, and emulsifiers

    • Synergizes well with Vitamin C, Vitamin E, ferulic acid, retinol, and UV filters like avobenzone


3. How to Incorporate Synoxyl® AZ into Formulations

  • Formulation Phase: Best added during the oil phase or cool-down phase depending on product type.

  • Processing Temperature: Recommended to be added below 40°C to preserve bioactivity.

  • Formulation Tip: Pre-dispersing Synoxyl® AZ in a carrier oil like caprylic/capric triglyceride or an ester can aid uniform distribution.

Key Considerations:

  • Maintain pH between 4–8 for optimal performance.

  • Use in combination with photounstable ingredients (like avobenzone or ascorbic acid) to boost longevity and protect actives from oxidation.


4. Where Synoxyl® AZ is Found in Skincare Products

Ideal for:

  • Antioxidant serums

  • Day and night moisturizers

  • Brightening treatments

  • UV-protective skincare (e.g., sunscreens and after-sun gels)

  • Eye creams targeting fine lines

  • Vitamin C and retinol-based formulas

Application Suggestions:

  • Use in AM formulas to protect skin from oxidative damage throughout the day.

  • Combine with SPF products to support photostability.

  • Blend into PM serums to aid overnight repair and reduce oxidative stress from the day.


Why Formulators Choose Synoxyl® AZ:
Its strong antioxidant profile, ability to stabilize volatile ingredients, and proven skin tone-evening effects make it a go-to for advanced anti-aging and protective skincare.


References:

  • Manufacturer’s Technical Data Sheet

  • Studies on Acetyl Zingerone’s efficacy as an antioxidant

  • Comparative antioxidant studies with Vitamin C and E derivatives