1. What is Synoxyl® AZ and How is it Used in Cosmetics?
Synoxyl® AZ is a patented, multifunctional skincare ingredient designed to target visible skin aging caused by environmental stress. Its key active, Acetyl Zingerone, is a scientifically engineered antioxidant inspired by zingerone, a bioactive molecule derived from ginger. Acetyl Zingerone is known for its superior free radical scavenging capabilities and exceptional photostability.
In cosmetic formulations, Synoxyl® AZ is prized for its ability to:
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Neutralize oxidative stress from UV and pollution.
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Protect against visible signs of photoaging.
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Stabilize light- and oxygen-sensitive ingredients (like Vitamin C and retinol).
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Enhance skin brightness and reduce the look of uneven tone.
Its multifunctional performance makes it ideal for clean, active-forward skincare formulations.
2. Synoxyl® AZ Technical Details and Characteristics
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INCI Name: Acetyl Zingerone
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CAS Number: 56984-25-9
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Appearance: Light yellow to amber powder or viscous liquid (form may vary by supplier)
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Solubility: Oil-soluble
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Recommended Usage Rate: 0.1% – 1.0%
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pH Stability: 4.0 – 8.0
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Functions:
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Potent antioxidant
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Skin-protectant
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Photostabilizer for UV filters and sensitive actives
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Brightening and tone-evening support
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Compatibility:
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Compatible with esters, natural oils, silicones, and emulsifiers
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Synergizes well with Vitamin C, Vitamin E, ferulic acid, retinol, and UV filters like avobenzone
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3. How to Incorporate Synoxyl® AZ into Formulations
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Formulation Phase: Best added during the oil phase or cool-down phase depending on product type.
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Processing Temperature: Recommended to be added below 40°C to preserve bioactivity.
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Formulation Tip: Pre-dispersing Synoxyl® AZ in a carrier oil like caprylic/capric triglyceride or an ester can aid uniform distribution.
Key Considerations:
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Maintain pH between 4–8 for optimal performance.
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Use in combination with photounstable ingredients (like avobenzone or ascorbic acid) to boost longevity and protect actives from oxidation.
4. Where Synoxyl® AZ is Found in Skincare Products
Ideal for:
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Antioxidant serums
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Day and night moisturizers
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Brightening treatments
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UV-protective skincare (e.g., sunscreens and after-sun gels)
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Eye creams targeting fine lines
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Vitamin C and retinol-based formulas
Application Suggestions:
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Use in AM formulas to protect skin from oxidative damage throughout the day.
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Combine with SPF products to support photostability.
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Blend into PM serums to aid overnight repair and reduce oxidative stress from the day.
Why Formulators Choose Synoxyl® AZ:
Its strong antioxidant profile, ability to stabilize volatile ingredients, and proven skin tone-evening effects make it a go-to for advanced anti-aging and protective skincare.
References:
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Manufacturer’s Technical Data Sheet
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Studies on Acetyl Zingerone’s efficacy as an antioxidant
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Comparative antioxidant studies with Vitamin C and E derivatives